Surgeons can now choose between titanium and PEEK for patient-specific cranio-maxillofacial reconstructions within a single workflow.

Material Choice for Patient-Specific Implants

Materialise has expanded its cranio-maxillofacial (CMF) portfolio to include PEEK (polyetheretherketone) implants, giving surgeons the flexibility to choose between titanium and PEEK for patient-specific reconstructions—all within a single digital workflow.

The Belgian company, a global leader in personalized medical solutions, announced the expansion on February 17, 2026. The custom-made PEEK implants are fully integrated into Materialise's established CMF ecosystem, which includes collaborative 3D planning, seamless case management, and fixation solutions.

Why PEEK Matters

PEEK offers distinct advantages for certain clinical indications:

  • Radiolucency: PEEK doesn't interfere with X-rays, CT scans, or MRI imaging—crucial for post-operative monitoring
  • Thermal conductivity: Lower thermal conductivity than titanium, reducing temperature sensitivity
  • Mechanical properties: Elastic modulus closer to bone, potentially reducing stress shielding
  • Lightweight: Lower density than titanium for patient comfort

"Personalization isn't just about material choices but about the precision of the planning process and the reliability of execution," said Maarten Zandbergen, Market Manager at Materialise. "Our clinical engineers work hand in hand with surgeons to design each implant."

One Workflow, Two Materials

The key advantage of Materialise's approach is workflow continuity. Surgeons can:

  • Plan a case in Mimics Enlight CMF software with dedicated clinical engineers
  • Manage the case through Mimics Flow
  • Choose the appropriate material—titanium or PEEK—based on clinical needs
  • Use the same validated, traceable process regardless of material choice

This eliminates the complexity of working with multiple suppliers for different materials and ensures consistent quality across all patient-specific implants.

What Can Be Treated?

The CMF portfolio supports reconstruction of:

  • Cranial vault: Skull defects from trauma, tumor resection, or congenital conditions
  • Mandible: Lower jaw reconstruction
  • Midface: Cheek, orbital, and nasal region reconstruction

Both porous 3D-printed titanium and milled PEEK options are available for cranial reconstruction specifically.

The Bigger Picture

This expansion reflects a broader trend in medical 3D printing: moving beyond proof-of-concept to integrated clinical workflows. Materialise has built its CMF business over decades, and adding PEEK demonstrates how mature the personalized implant market has become.

For surgeons, having material choice within a single validated workflow simplifies clinical decision-making. For patients, it means access to implants tailored to both their anatomy and their specific clinical needs.

The company's CMF solutions are CE-marked and ISO-certified, with clinical engineer collaboration available to tailor every implant to the surgical approach.

Source: Materialise NV

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